名称 | Human IgG2 CH23 Protein |
纯度 | >95% as determined by SDS-PAGE&HPLC |
表达宿主 | 293 Cells |
标签 | His |
种属 | Human |
分子量 | 32 kDa |
缓冲液 | 50mM Tris, 300mM NaCl, 5%Sucrose, PH:8.5 |
稳定性 & 储存条件 |
-80 ℃ packaging and storage to avoid repeated freezing and thawing. |
SDS-PAGE | |
HPLC |
The human IgG2 CH23 protein is an important component of the human immune system, derived from the IgG2 subclass of immunoglobulins. IgG2 antibodies play a crucial role in regulation and complement activation, aiding in the neutralization of pathogens. The IgG2 Fc region, including CH2 and CH3 domains, has been studied for its structural changes during Fc conformational changes. The CH2-CH3 interface is highly conserved and plays a functional role in regulating the binding of FcγR and other proteins to Fc. This protein fragment is typically expressed in HEK293 cells and used for various biomedical applications, including research, diagnosis, and treatment. Its high specificity and affinity make it a valuable tool for studying immune responses and developing new therapies for diseases.
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