| 名称 | Human IgG3 CH23 Protein |
| 纯度 | ＞90% as determined by SDS-PAGE&HPLC |
| 表达宿主 | 293 Cells |
| 标签 | His |
| 种属 | Human |
| 分子量 | 32 kDa |
| 缓冲液 | 50mM Tris, 300mM NaCl, 5%Sucrose, PH:8.5 |
| 稳定性 & 储存条件 |
-80 ℃ packaging and storage to avoid repeated freezing and thawing. |
| SDS-PAGE |
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| HPLC |
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Immunoglobulin G3 (IgG3) is a member of immunoglobulin G produced and secreted by many effective B cells. After gastric protease cleavage, IgG is divided into two F (ab) fragments, each with an antigen binding site and a highly conserved Fc fragment. The Fc segment has highly conserved N-glycosylation sites. The C region of the Igγ-3 chain (IgG3 Fc/IGHG3) contains two constant regions (CH2, CH3) of the IgG3 H chain. The CH23 domain is crucial for its function, as its glycosylation and charge characteristics affect its affinity. Mouse IgG3 has potential therapeutic applications, particularly in the development of chimeric antibodies for infectious diseases.
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