| 名称 | Metalloproteinase inhibitor 1 Protein |
| 纯度 | >85% |
| 宿主细胞 | HEK293 |
| 序列 | MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIA |
| 基因名 | TIMP1 |
| Uniprot ID | Q5RC60 |
| 物种 | Pongo abelii(Sumatran orangutan) |
| 产品性状 | Liquid |
| 缓冲液 | 1×PBS，pH7.4 |
| 储存方式 | -80 ℃ packaging and storage to avoid repeated freezing and thawing. |
| SDS-PAGE &WB |
|
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity).
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